Arom. aldehydes, e.g., vanillin, having electron-releasing para substituents, such as a hydroxy group, are carbonylated to phenylacetic acid derivs. in the presence of a Pd-PPh3-HCl catalytic system, at 90-120°, 50-100 atm of carbon monoxide, 1-2 h, in the presence of water or an alkanol. PPh3 and HCl play key roles in the catalysis, since in their absence no activity is obsd.
|Data di pubblicazione:||1991|
|Titolo:||Carbonylation of aromatic aldehydes to phenylacetic acid derivatives catalyzed by a palladium-triphenylphosphinehydrogenchloride system|
|Rivista:||JOURNAL OF MOLECULAR CATALYSIS|
|Digital Object Identifier (DOI):||http://dx.doi.org/10.1016/0304-5102(91)80111-F|
|Appare nelle tipologie:||2.1 Articolo su rivista |