The ozonation of 4-thiopyrimidine and 6-thiopurine nucleosides in presence of amines afforded selectively and under mild experimental conditions several cytidine and adenosine nucleosides. The same reaction carried out in presence of alcohols afforded O-4- or O-6-alkylated derivatives of the nucleosides.

OZONATION OF THIONUCLEOSIDES - A NEW CHEMICAL TRANSFORMATION OF 4-THIOURACIL AND 6-THIOGUANINE NUCLEOSIDES TO CYTOSINE AND ADENOSINE COUNTERPARTS

CRESTINI, Claudia;
1995-01-01

Abstract

The ozonation of 4-thiopyrimidine and 6-thiopurine nucleosides in presence of amines afforded selectively and under mild experimental conditions several cytidine and adenosine nucleosides. The same reaction carried out in presence of alcohols afforded O-4- or O-6-alkylated derivatives of the nucleosides.
1995
51
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10278/3710122
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