Advanced Electrochemical and Opto-Electrochemical Biosensors for Quantitative Analysis of Disease Markers and Viruses

Instrumental laboratory methods for biochemical and chemical analyses have reached a high level of reliability with excellent sensitivity and specificity. However, the complex sample preparation, the need for trained personnel as well as the use of sophisticated and expensive instrumentation still represent a drawback. Despite the indispensability of laboratory methods that guarantee excellence with regard to their analytical reliability, the need to carry out quantitative analyses for large-scale and rapid screening purposes has prompted the development of novel analytical tools, such as biosensors, capable of providing accurate and precise analytical information at low cost, ease of use and applicability for decentralized monitoring and point-of-care testing. The recent global health crisis caused by the COVID-19 pandemic has further alerted the world to the urgent need for rapid and reliable analytical devices, which are suitable for the detection of biologically active components of clinical relevancy.